Chronic Viral and Inflammatory Cardiomyopathy (eBook)

Preface 5
Contents 9
I Chronic Viral and Inflammatory Cardiomyopathy 18
1 Overview on Chronic Viral Cardiomyopathy/Chronic Myocarditis 19
2 Unsolved Medical Issues and New Targets for Further Research in Viral Myocarditis and Dilated Cardiomyopathy 35
II Viruses 52
3 Frontiers in Viral Diagnostics 53
4 Invited for Debate: Is Virus Persistence a Determinant for Disease Progression? 69
5 Parvovirus B19: The Causative Agent of Dilated Cardiomyopathy or a Harmless Passenger of the Human Myocard? 76
6 Parvovirus B19: A New Emerging Pathogenic Agent of Inflammatory Cardiomyopathy 96
7 Role of Hepatitis C Virus in Cardiomyopathies 111
III Immunity and Autoimmunity 133
8 Recent Insights into the Role of Host Innate and Acquired Immunity Responses 134
9 The Significance of Autoimmunity in Myocarditis 151
10 The Roles of Immunity and Autoimmunity in Chronic Heart Failure 165
11 Clinical Implications of Anti-cardiac Immunity in Dilated Cardiomyopathy 179
IV Cardiac Remodeling 204
12 Inflammation and Cardiac Remodeling During Viral Myocarditis 205
13 Inflammatory Cardiomyopathy: There Is a Specific Matrix Destruction in the Course of the Disease 227
14 Invited for Debate: Is There a Virus-Specific Matrix Destruction in the Course of Disease in Dilated Cardiomyopathy? 259
V Diagnosis and Treatment 266
15 New Non-invasive Approaches for the Diagnosis of Cardiomyopathy: Magnetic Resonance Imaging 267
16 New Therapeutics Targets in Chronic Viral Cardiomyopathy 292
17 Myocarditis and Inflammatory Cardiomyopathy: Histomorphological Diagnosis 309
18 Anti-viral Treatment in Patients with Virus-Induced Cardiomyopathy 326
19 Immunosuppressive Treatment of Chronic Non-viral Myocarditis 346