Membrane Toxicity

Section I. Xenobiotics and Membrane Transport.- Effect of P-Chloromercuribenzoate (pCMB), Ouabain and 4-Acetamido-4?ISO-Thiocyamatostilbene-2,2?-Disulfonic Acid (Sits) on Proximal Tubular Transport Processes.- Heavy Metals and Membrane Functions of an Alveolar Epithelium.- The Localization of Ion-Selective Pumps and Paths in the Plasma Membranes of Turtle Bladders.- Membrane Water Channels and SH-Groups.- Membrane Transport of Antifolates as a Critical Determinant of Drug Cytotoxicity.- Section II. Modification of Membrane Function by Toxicological Agents.- Liver Endoplasmic Reticulum: Target Site of Halocarbon Metabolites.- The Role of Membrane Damage in Radiation-Induced Cell Death.- Mechanisms by Which Small Molecules Alter Ionic Permeability Through Lipid Bilayer Membranes.- Effects of Neomycin on Polyphosphoinositides in Inner Ear Tissues and Monomolecular Films.- High Affinity SH-Groups on the Surface of Pancreas Cells Involved in Secretin Stimulation.- Section III. Cellular Responses to Toxins.- Cell Membranes in Cytotoxicity.- Altered Drug Permeability in Mammalian Cell Mutants.- Lectin Receptors and Lectin Resistance in Chinese Hamster Ovary Cells.- Biological Applications and Evolutionary Origins of Ionophores.- Penicillin-Binding Proteins of Bacteria.- Section IV. Toxic Chemicals as Molecular Probes of Membrane Structure and Function.- Toxic Chemical Agents as Probes for Permeation Systems of the Red Blood Cell.- Chemical and Enzymatic Modification of Membrane Proteins and Anion Transport in Human Red Blood Cells.- On the Nature of the Transport Pathway Used for Ca-Dependent K Movement in Human Red Blood Cells.- Toxic Chemicals as Probes of Nerve Membrane Function.- Section V. Effects on Membranes and Receptors.- Interactions of Acetylcholine Receptors with Organic Mercury Compounds.- Lead Actions on Sodium-Plus-Potassium-Activated Adenosinetriphosphatase from Electroplax, Rat Brain, and Rat Kidney.- Lipid Model Membrane Studies on Immune Cytotoxic Mechanisms.- Diffusional Transport of Toxic Materials in Membranes Studied by Fluorescence Spectroscopy.- Author Index.