Focus on Genetic Screening Research
Seiten
2006
Nova Science Publishers Inc (Verlag)
978-1-60021-229-1 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-60021-229-1 (ISBN)
Gene tests, the sophisticated of the techniques used to test for genetic disorders, involve direct examination of the DNA molecule. Other genetic tests include biochemical tests for such gene products as enzymes and other proteins and for microscopic examination of stained or fluorescent chromosomes. This book gathers research in this field.
Gene tests (also called DNA-based tests), the newest and most sophisticated of the techniques used to test for genetic disorders, involve direct examination of the DNA molecule itself. Other genetic tests include biochemical tests for such gene products as enzymes and other proteins and for microscopic examination of stained or fluorescent chromosomes. Genetic tests are used for several reasons, including: Carrier screening, which involves identifying unaffected individuals who carry one copy of a gene for a disease that requires two copies for the disease to be expressed; Preimplantation genetic diagnosis prenatal diagnostic testing new-born screening; Presymptomatic testing for predicting adult-onset disorders such as Huntington's disease; Presymptomatic testing for estimating the risk of developing adult-onset cancers and Alzheimer's disease; Confirmational diagnosis of a symptomatic individual forensic/identity testing. In gene tests, scientists scan a patient's DNA sample for mutated sequences. A DNA sample can be obtained from any tissue, including blood. For some types of gene tests, researchers design short pieces of DNA called probes, whose sequences are complementary to the mutated sequences. These probes will seek their complement among the three billion base pairs of an individual's genome. If the mutated sequence is present in the patient's genome, the probe will bind to it and flag the mutation. Another type of DNA testing involves comparing the sequence of DNA bases in a patient's gene to a normal version of the gene. This book gathers important research in this field.
Gene tests (also called DNA-based tests), the newest and most sophisticated of the techniques used to test for genetic disorders, involve direct examination of the DNA molecule itself. Other genetic tests include biochemical tests for such gene products as enzymes and other proteins and for microscopic examination of stained or fluorescent chromosomes. Genetic tests are used for several reasons, including: Carrier screening, which involves identifying unaffected individuals who carry one copy of a gene for a disease that requires two copies for the disease to be expressed; Preimplantation genetic diagnosis prenatal diagnostic testing new-born screening; Presymptomatic testing for predicting adult-onset disorders such as Huntington's disease; Presymptomatic testing for estimating the risk of developing adult-onset cancers and Alzheimer's disease; Confirmational diagnosis of a symptomatic individual forensic/identity testing. In gene tests, scientists scan a patient's DNA sample for mutated sequences. A DNA sample can be obtained from any tissue, including blood. For some types of gene tests, researchers design short pieces of DNA called probes, whose sequences are complementary to the mutated sequences. These probes will seek their complement among the three billion base pairs of an individual's genome. If the mutated sequence is present in the patient's genome, the probe will bind to it and flag the mutation. Another type of DNA testing involves comparing the sequence of DNA bases in a patient's gene to a normal version of the gene. This book gathers important research in this field.
Preface; Screening for Cystic Fibrosis Mutations in Southern European Countries: Methods for Molecular Diagnosis, Prenatal Diagnosis and Carrier Identification Amongst High-Risk Individuals -- The Greek Experience; Anxiety of Pregnant Women After Prenatal Amniocentesis Genetic Testing; Mendelian Disorders Among Jews and Population Screening for Reproductive Purposes; Polymorphisms of Human Platelet Receptor Genes: Clinical Relevance and Diagonostic Application of Genotyping; New Approach for Important Factor Selection From High Dimensional Bioinformatics Data; Application of Microsatellite Marker Analysis; Index.
Erscheint lt. Verlag | 1.6.2006 |
---|---|
Zusatzinfo | Illustrations, unspecified |
Verlagsort | New York |
Sprache | englisch |
Maße | 260 x 180 mm |
Gewicht | 578 g |
Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik |
ISBN-10 | 1-60021-229-8 / 1600212298 |
ISBN-13 | 978-1-60021-229-1 / 9781600212291 |
Zustand | Neuware |
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