Pharmacology and Ototoxicity for Audiologists

Kathleen Campbell, Ph.D., is Professor and Director of Audiology Research at Southern Illinois University School of Medicine in Springfield, Il. She directed and provided audiology services for over 20 years in Canada and the United States but now focuses primarily on both basic and clinical research. For over 20 years, she has also taught audiology to faculty, residents, and medical students in otolaryngology, pediatrics, neurology, primary care, neonatology, and surgery. She is the author of Essential Audiology for Physicians and numerous book chapters and articles. She currently serves on the American Academy of Audiology Board of Directors. She consults in audiology clinical management, clinical trials, and as an expert witness. Dr. Campbell is also a prolific researcher, publishing numerous articles on both basic science and clinical topics in various areas of auditory science and auditory disorders. She is a noted lecturer both nationally and internationally focusing on audiologic assessment of auditory disorders, and particularly ototoxicity, noise-induced hearing loss and otoprotective agents. She has received an NIH Clinical Investigator Development Award, the James A. Shannon Director¿s Award from NIH for her research in ototoxicity, a Special Presidential Citation from the American Academy of Audiology for her work in Professional Practice Standards, has been named an ASHA Fellow and is in Who¿s Who in America. Dr. Campbell also holds several patents for otoprotective agents and is planning clinical trials. Dr. Campbell recently received the 2004 Copper Black Award for Creative Achievement from American Mensa for her work in otoprotective agents.

Overview
Pharmacology
Chapter 1: Michael Meldrum, PhD, Pharmacodynamics University of Florida: Introduction to Pharmacology
Chapter 2: Jose Rey PharmD: Pharmacokinetics and Pharmacodynamics, dose response considerations
Chapter 3: Tabitha Parent Buck, AuD; Henry P. Trahan, AuD; O.T. Wendel, PhD: Pharmacotherapeutics and Patient Factors
Chapter 4: Venkatesh Atul Bhattaram, PhD Rajanikanth Madabushi,PhD and Hartmut Derendorf, PhD The Food and Drug Administration and the Drug Approval Process
Chapter 5: Karen Doyle, MD: Common Classes of Drugs used in Otolaryngologic Practice
Chapter 6: Michael Seidman, MD: Nutraceuticals and Herbal Supplements (Including the DSHEA act)
Chapter 7: Richard Bobbin, PhD, Jean Luc Puel, and Post Doc: Mechanisms of Toxicity including physical, free radical: Oxidative and Anti-oxidative Mechanisms, protein interactions, and defense mechanisms
Chapter 8: Sandra McFadden, PhD: Biochemical Bases of Hearing including cochlear biochemistry, overview of neurotransmitters and neurotransmitters of the auditory System
Chapter 9: A.U. Bankaitis,PhD, Robert J. Kemp, MBA Infection Control in the Audiology Clinic"
Drug and Noise-induced Ototoxicity
Chapter 10: Len Rybak, MD, PhD, Xinyan Huang, MD and Kathleen Campbell, PhD: Cancer and Ototoxicity of Chemotherapeutics
Chapter 11: Jochen Schacht, PhD Aminoglycoside Ototoxicity: review of actions and aminoglycoside Antibiotic Ototoxicity
Chapter 12: Len Rybak MD, PhD: Renal function and Ototoxicity of Loop Diuretics
Chapter 13: Brenda Lonsbury Martin: Temporary and permanent ototoxicity of aspirin, quinine, non-steroidal anti-inflammatory drugs, and the macrolides
Chapter 14: Benoît Pouyatos PhD, Larry Fechter, PhD: Industrial Chemicals and Solvents affecting the Auditory System
Chapter 15: Don Henderson, PhD: Cellular Mechanisms of Noise-Induced Hearing Loss
Chapter 16: Barbara Cone-Wesson, PhD: Alcohol, Drug Exposure, and Nutritional Influences on Hearing and Speech Development
Chapter 17: Steve Fausti, PhD: Audiologic Monitoring for Ototoxicity and Patient Management
Chapter 18: Owen Black, MD, Susan Pesznecker RN: Mechanisms of Vestibular Toxicity including review of nausea and vomiting
Chapter 19: Jaynee Handelsman, PhD: Audiologic Findings in Vestibular Toxicity
New Directions:
Chapter 20: Kathleen Campbell PhD and Len Rybak, MD, PhD: Otoprotective and Rescue Agents
Chapter 21: Brenda Ryals, PhD: Regeneration of Hair Cells
Chapter 22: Sharon Kujawa PhD and William Sewell PhD: Using Drugs as Tools to Investigate the Auditory System
Chapter 23: Robert DiSogra AuD Staying Current: Websites and Resources for Pharmaceutical Information, Patient Support Groups and Organizations"