Immunobiology Of Natural Killer Cells

Dr. Eva Lotzova is Professor of Immunology, Chief of the Division of Immunologenetics at the University of Texas System Cancer, M.D. Anderson Hospital and Tumor Institute, Houston. Dr. Ronald B. Herberman, formerly Chief of Biological Therapeutics Branch and Acting Associate Director for the Biological Response Modifiers Program, Division of Cancer Treatment, National Cancer Institute, Frederick, Maryland.

1. Assays for NK Cell Cytotoxciity; Their Values and Pitfalls 2. Separation and Characterization of Phenotypically Distinct Subsets of NK Cells 3. Ultrastructure and Cytochemistry of the Human Large Granular Lymphocytes 4. Phylogeny and Ontogeny of NK Cells 5. Tissue and Organ Distribution of NK Cells 6. Genetic Control of NK Cell Activity in Rodents 7. Phenotype, Functional Heterogenecity, and Lineage of Natural Killer Cells 8. Target Cell Structures, Recognition Sites, and the Mechanism of NK Cytotoxicity 9. Natural Killer Cytotoxic Factors (NKCF) Role in Cell-Mediated 10. Characteristics of Cultured NK Cells 11. Lectin-Dependent Killer Cells 12. MLC-Induced Cytoxicity as a Model for the Development and Regulation of NK Cytotoxicity 13. LGL Lymphoproliferative Diseases in Man and Experimental Animals: The Characteristics of These Cells and Their Potential Experimental Uses