Interleukin-5
Marcel Dekker Inc (Verlag)
978-0-8247-0190-1 (ISBN)
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This important volume describes the latest advances in all areas of interleukin-5 (IL5) research, pooling the insights of over 65 biological researchers, pharmaceutical scientists, and clinicians, representing institutions as diverse as the Mayo Clinic, the National Lung and Heart Institute, the John Curtin School of Medical Research, the Geneva Biomedical Research Institute, the Flanders' Interuniversity Institute for Biotechnology, and the University of Tokyo.
Details IL5-related antiallergy drugs currently in development at Glaxo Wellcome and Schering-Plough Research Institute!
Reviewing approaches toward small molecule antagonists and inhibitors, Interleukin-5
highlights the structure and function of IL5 and IL5 receptors
explores the interaction between IL5 and eotaxin
analyzes agents that down-regulate IL5 production
evaluates studies on IL5 knockout and transgenic mice
outlines the regulation of IL5 gene expression
discusses the protein structure of IL5
covers the signalling pathways used by the IL5 receptor
relates the structure and role of receptor subunits in signal transduction
and more!
Featuring over 1250 references, tables, drawings, photographs, and micrographs, Interleukin-5 is suitable for pulmonologists and pulmonary disease specialists; immunologists; clinical allergists; internists; chest, intensive care, primary care, and family practice physicians; respiratory therapists; physiologists; pathologists; cell and molecular biologists; and medical school students in these disciplines.
The Eosinophil and Bronchial Asthma: Evidence for a Critical Role of Eosinophils in Pathophysiology, Gerald J. Gleich and Cheryl R. Adolphson
Interleukin-5 in Rhinitis: Influence of Treatment, Stephen R. Durham, Keisuke Masuyama, and Qutayba Hamid
Interleukin-5 and Interleukin-5 Receptor in Asthma, Douglas S. Robinson
Bone Marrow in Allergic Disease: The Role of Interleukin-5 as an Eosinophilopoietic Factor, Roma Sehmi and Judah A. Denburg
Eosinophils, Interleukin-5, and Cutaneous Disease, Kristin M. Leiferman
Perinatal and Early Childhood Cytokine Responses to Environmental Allergens, Claudia Macaubas, Susan L. Prescott, Troy Smallacombe, Akihiro Yabuhara, Thierry Venaille, Barbara Holt, Peter D. Sly, and Patrick Holt
The Role of Interleukin-5 in Allergic Airways Disease, Paul S. Foster, Simon P. Hogan, Klaus I. Matthaei, and Ian G. Young
Cytokine Control of the Development of a T-Helper 2 Response, Andrew N. J. McKenzie
Interactions Between Interleukin-5 and the Eosinophil-Selective Chemokine Eotaxin: Potential Relevance in Allergic Disease, Paul D. Collins and Timothy J. Williams
Structure of Interleukin-5, Irwin M. Chaiken and Amanda E. I. Proudfoot
The Structural Basis for Interleukin-5 Receptor Assembly, Christopher J. Bagley, Joanna M. Woodcock, Frank C. Stomski, and Angel F. López
Analysis of the Expression Pattern of Human Interleukin-5 Receptor Isoforms In Vitro, Jan Tavernier, Annick Verhee, Joël Vandekerckhove, Xaveer Van Ostade, and José Van der Heyden
Role of the Common Subunit of the Interleukin-3, Interleukin-5, and Granulocyte Macrophage-Colony Stimulating Factor Receptors, Atsushi Miyajima, Taisei Kinoshita, and Takahiko Hara
Interleukin-5 Receptor and Signal Transduction, Kiyoshi Takatsu
Regulation of Interleukin-5 Gene Expression, Colin J. Sanderson, Monica L. De Boer, Monica Senna Salerno, Gretchen T. F. Schwenger, Marc Thomas, Viatcheslav A. Mordvinov, and Stéphane Karlen
Regulation of Interleukin-5 Expression in T Lymphocytes: Repression by Dexamethasone, Ian G. Young,Chiok L. Tan, Juliet A. Fisher, Barbara H. van Leeuwen, and Klaus I. Matthaei
Interleukin-5 and the Interleukin-5 Receptor: Targets for Drug Discovery in Asthma, Murray McKinnon, Martyn Banks, Roberto Solari, and Graeme Robertson
Pulmonary Biology of Anti-Interleukin-5 Antibodies, Robert W. Egan, Chuan-Chu Chou, Richard W. Chapman, Chung-Her Jenh, Ted T. Kung, Peter J. Mauser, Diljeet Athwal, J. Spencer Emtage, and Mark W. Bodmer
| Reihe/Serie | Lung Biology in Health and Disease |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 216 x 279 mm |
| Gewicht | 726 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Pneumologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| ISBN-10 | 0-8247-0190-9 / 0824701909 |
| ISBN-13 | 978-0-8247-0190-1 / 9780824701901 |
| Zustand | Neuware |
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