Horizons in Cancer Research

This book presents original results on the leading edge of cancer research. Chapter One provides a brief overview of the recent updates in the role of the laboratory in establishing the diagnosis, methods of disease monitoring and mechanisms that contribute to tyrosine kinase inhibitor (TKI) resistance for patients with chronic myeloid leukemia. Chapter Two reviews self-esteem and academic difficulties in preadolescents and adolescents health from pediatric leukemia. Chapter Three analyses the role of lactoferrin expression in the initiation and progression of most common hormone-dependent cancers. Chapter Four studies the ETS transcription factor FLI-1 as an important player in human cancer. Chapter Five highlights the latest advances in DNA methylation signature- based liquid biopsy. Chapter Six presents data concerning the pharmacological activity of water-soluble complex of quercetin with polyvinylpyrrolidone on the process of bleomycin-induced lung fibrosis in mice. Chapter Seven investigates prospects of enhancing anti-cancer activities of quercetin in the treatment of glioblastoma. Chapter Eight discusses the correction of tumor-associated thrombocytopenia by quercetin. Chapter Nine examines robotic surgery for prostate cancer.