Für diesen Artikel ist leider kein Bild verfügbar.

Renal Disposition and Nephrotoxicity of Xenobiotics

Buch | Hardcover
342 Seiten
1993
Academic Press Inc (Verlag)
978-0-12-057730-9 (ISBN)
98,50 inkl. MwSt
  • Titel ist leider vergriffen;
    keine Neuauflage
  • Artikel merken
Summarizes the current knowledge about the mechanisms of the renal handling of xenobiotic metabolites and the mechanism by which xenobiotics produce nephrotoxicity. The multidisciplinary approach should enhance the understanding of the renal disposition and nephrotoxicity of xenobiotics.
This volume summarizes the current knowledge about the mechanisms of the renal handling of xenobiotic metabolites and the mechanism by which xenobiotics produce nephrotoxicity. It focuses on three areas - the assessment of xenobiotic-induced nephrotoxicity, the renal disposition of xenobiotics, and the bioactivation and nephrotoxicity of xenobiotics. The authors represent several fields of specialization, and the multidisciplinary approach taken should enhance the understanding of the renal disposition and nephrotoxicity of xenobiotics.

Part 1 Assessment of xenobiotic-induced nephrotoxicity: isolated renal cells in the study of nephron heterogeneity and nephrotoxicity, L.H. Lash; the use of cultured renal epithelial cells "in vitro" assessment of xenobiotic-induced nephrotoxicity, G. Gstraunthaler and W. Pfaller; epithelial cell fusion of normal and pH-transformed madin darby canine kidney cells - new tool for studying mechanisms of carcinogenesis, H. Oberleithner; NMR - a tool for the study of renal function and nephrotoxicity, B.D. Ross and J.C. Bellinger. Part 2 Renal disposition of xenobiotics: interaction of xenobiotics with organic anion and cation transport systems in renal proximal tubule cells, K.J. Ullrich, et al; renal transport of heavy metals, E.C. Foulkes; renal transport and metabolism of mercapturic acids and their precursors, the S-conjugates of glutathione and cysteine, S. Silbernagl and A. Heuner; renal xenobiotic metabolism - role in bioactivation of nephrotoxic xenobiotics. Biactivation and nephrotoxicity of xenobiotics, M.W. Anders and W. Dekant; bioactivation of halogenated xenobiotics by S-conjugate formation, W. Dekant, et al; a2h-globulin-related nephrotoxicity, E.A. Lock; cyclosporin A induced nephrotoxicity - current concepts and controversies, P.H. Whiting; the renal tubular transport and nephrotoxicity of beta-lactam antibiotics, B.M. Tune; the nephrotoxicity of heavy metals, W.O. Berndt; the nephrotoxicity of anticancer drugs, R.F. Borch; hormone-induced nephrocarcinogenicity, M. Metzler; nephrocarcinogenicity of haloalkenes and alkynes, S. Vamvakas, et al.

Zusatzinfo references, index
Verlagsort San Diego
Sprache englisch
Gewicht 690 g
Themenwelt Studium 2. Studienabschnitt (Klinik) Pathologie
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
ISBN-10 0-12-057730-5 / 0120577305
ISBN-13 978-0-12-057730-9 / 9780120577309
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich

von Gerald Höfler; Hans Kreipe; Holger Moch

Buch | Hardcover (2024)
Urban & Fischer in Elsevier (Verlag)
104,00

von Thomas Kirchner; Hans Konrad Müller-Hermelink …

Buch | Softcover (2023)
Urban & Fischer in Elsevier (Verlag)
42,00
Klinisch-pathologische Übersichtskarten

von Thomas Cerny; Kirill Karlin

Buch | Hardcover (2023)
Springer (Verlag)
34,99