Leukaemia

Section 1: Aetiology : Epidemiology; Leukaemogenic viruses; The genetics of human leukaemia; Experimental leukaemia; Leukaemia kinetics. Section 2: Pathology and pathophysiology : Clonal analysis of haemopoietic cell development; Classification, morphology and cytochemistry of acute leukaemias; Cytogenetics; Cell surface differentiation markers; Glucocorticoid receptors; Myelodysplasia and preleukaemia: pathogenesis and functional aspects. Section 3: Clinical aspects : general considerations : Supportive care with blood and platelet transfusions; Management of infection in leukaemic patients; Principles of leukaemia treatment. Clinical features and management : Acute myeloid leukaemia: clinical features and management; Acute myeloid leukaemia: prognostic factors; The acute lymphoblastic leukaemias; The chronic myeloid leukaemias; The chronic lymphoid leukaemias; Hairy-cell leukaemia; Myelodysplasia: morphology, clinical presentation and treatment; Secondary leukaemias; Bone marrow transplantation for the treatment of leukaemia. Clinical trials and future trends : Design of clinical trials; Future trends.