New Concepts in Cerebral Ischemia

Offering a description of the techniques and theories employed in both basic and clinical research, this book delineates the mechanisms underlying neuronal damage induced by ischemia. It covers methods to elucidate the pathogenesis of ischemia, and technologies used in the design of specific strategies to protect neurons from further injury.

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Approximately half a million Americans suffer brain ischemic episodes every year. These brain strokes are the third leading cause of death in the United States and the number-one cause of permanent disability. Over the past decade, we have made extensive attempts to understand the biological mechanisms that underlie stroke-induced neuronal injury. This research has been benefited by the introduction of a variety of new technologies and assays aimed at deciphering the complex neuronal degenerating processes triggered by cerebral vascular disorders or other neurological diseases that produce ischemic episodes.

New Concepts in Cerebral Ischemia presents techniques and theories for understanding the various stages of early pathogenesis in order to design specific strategies to protect neurons from further injury. Short, specific, and comprehensive chapters provide detailed descriptions of the new methods employed in both basic and clinical research that are revolutionizing the field of ischemia research. Written by international experts in CNS dysfunction, the book includes methods to elucidate the pathogenesis of ischemia, technologies used in the design of specific strategies to protect neurons from further injury, and new approaches to treat patients with acute ischemic episodes. With this book, you will gain new insights not only into cerebral vascular research, but also into neurological disease in general.