International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, November 13 to 15, 1969 (eBook)

Front Cover 1
International Symposium on the Treatment of Carcinoma of the Prostate Berlin, November 13 to 15,1969 4
Copyright Page 5
Table of Contents 6
Introductions 10
Chapter 1. Basis of Hormonal Treatment of Prostatic Cancer 12
References 15
Chapter 2. Hormonal Treatment of Cancer of the Prostate Pharmacological Aspects 18
References 29
Discussion 31
Chapter 3. The Metabolism of Testosterone in the Prostate 32
References 38
Discussion 38
Chapter 4. Pharmacological Aspects on the Treatment of Prostatic Carcinoma with Stilbestrol Diphosphate 40
References 45
Discussion 46
Chapter 5. Pathology of Cancer of Prostate 50
1. Introduction 50
2. Criteria for pathological diagnosis of carcinoma of the prostate 51
3. Lesions that simulate carcinoma of prostate (Fig. 18-24) 61
4. Grading of carcinoma of prostate 65
5. Location of the tumor and its significance in the choice of biopsy for diagnosis of carcinoma 65
6. Comparison of clinical and pathological flndings 66
7. Factors that may affect the prognosis 67
References 68
Discussion 69
Chapter 6.The Incidence of Cardiovascular Complications in Prostatic Cancer 74
1. Material and methods 75
2. Survival rates and causes of death 76
3. Relief of Cancer Symptoms 77
4. Cardiovascular Status 78
5. Discussion 83
References 84
Discussion 85
Chapter 7. Methods of Hormonal Treatment including Orchiectomy and Adrenalectomy 90
References 100
Chapter 8. Total Perineal Prostatectomy in 398 Patients with Cancer of the Prostate 102
Discussion 110
Chapter 9. Modern Radiotherapy of Prostatic Cancer 120
1. Patient selection 122
2. Stanford technique 122
3. Results 125
4. Complications 128
References 130
Discussion 130
Chapter 10. The Use of Radioactive Isotopes in the Management of Prostatic Cancer 134
References 148
Discussion 149
Chapter 11. Irradiation of the Hypophysis for advanced Cancer of the Prostate with Metastases 150
1. Technique 150
2. Results 151
3. Symptomatic response 152
4. Age 152
5. Complications 152
Discussion 153
Chapter 12. Cytotoxic Agents in the Treatment of Prostatic Carcinoma 154
References 162
Discussion 163
Chapter 13. Experiences with Cyproterone Acetate and Related Drugs in theTreatment of Prostatic Disease 170
Cyproterone Acetate Treatment of Disseminated Prostatic Cancer and Benign Nodular Hyperplasia 170
Chapter 14. Treatment of Benign Prostatic Hypertrophy with Progestogens including Gestonorone Caproate 174
Results 176
Discussion 178
References 181
Chapter 15. Panel Discussion 192
Hormone dosage 192
Sexual potency after total prostatectomy 193
Incontinence following radical prostatectomy 194
Surgical treatment of incontinence 195
Prevention of incontinence 196
Radical prostatectomy and orchiectomy 196
Therapeutic principles in the different stages of prostatic cancer 197
Subcapsular versus total orchiectomy 199
Surgical mortality 199
Cryo-therapy 200
Pathological grading of prostatic cancers 200
Radical retropubic prostatectomy following open perineal biopsy 202
Oestrogen, orchiectomy and combined therapy 203
Frequency of prostatic cancer 204
Early diagnosis of prostatic cancer 205
Prevention of suspected cardio-vascular complications 205
Testosterone shock therapy 206
Staging 207
Occult carcinoma 208
Stage A cancer 208
Timing of radical prostatectomy 210
Stage . cancer 210
Stage C cancer 211
Stage D cancer 213
Closing Addresses 215
Participants 216
» Advances in the Biosciences 220