Fetal and Neonatal Brain Injury

List of contributors; Foreword; Preface; Part I. Epidemiology, Pathophysiology and Pathogenesis of Fetal and Neonatal Brain Injury: 1. Perinatal asphyxia: an overview; 2. Mechanisms of brain damage in animal models of hyopoxia-ischemia in newborns; 3. Cellular and molecur biology of perinatal hypoxia-ischemic brain damage; 4. Fetal response to asphyxia; 5. Congenital malformations of the brain; 6. Prematurity and complications of labor and delivery; 7. Intrauterine growth retardation (restriction); 8. Hemorrhagic lesions of the central nervous system; Part II. Pregnancy, Labor, and Delivery Complications Causing Brain Injury: 9. Maternal diseases that affect fetal development; 10. Antepartum evaluation of fetal well-being; 11. Intrapartum evaluation of the fetus; 12. Obstetrical conditions and practices that affect the fetus and newborn - Section I and II; 13. Fetal and neonatal brain injury as a consequence of maternal substance abuse; 14. Chorioamnionitis and its possible relation top subsequent cerebral palsy; 15. Bacterial sepsis in the neonate; 16. Neonatal bacterial meningitis; 17. Neurological sequelae of congenital perinatal infection; 18. Perinatal human immunodeficiency virus infection; 19. Inborn errors of metabolism with featgures of hypoxic-ischemic encephalopathy; Part III. Diagnosis of the Infant with Asphyxia: 20. Clinical manifestations of hypoxic-ischemic encephalopathy; 21. The use of the EEG in assessing acute and chronic brain damage in the newborn; 22. Structural and functional imaging of hypoxic-ischemic injury (HII) in the fetal and neonatal brain; 23. Near-infrared spectroscopy and imaging; 24. Placental pathology and the etiologu of fetal and neonatal brain injury; 25. Correlations of clinical, laboratory, imaging and placental findings as to the timing of asphyxial events; Part IV. Specific Conditions Associated with Fetal and Neonatal Brain Injury: 26. Hypoglycemia in the neonate; 27. Hyperbilirubenemia and kernicterus; 28. Polycythemia; 29. Hydrops fetalis; 30. Acidosis/alkalosis; 31. Meconium staining and the meconium aspiration syndrome; 32. Persistent pulmonary hypertension of the newborn; 33. Pediatric cardiac surgery: relevance to fetal and neonatal brain injury; Part V. Management of the Depressed or Neurologically Dysfunctional Neonate: 34. Neonatal resuscitation: immediate management; 35. Extended management; 36. Neuroprotective mechanisms after hypoxic-ischemic injury; 37. The Management of neonatal seizures; 38. Use of a simulated program in the education of neonatal resuscitation; 39. Nutritional support of the asphyxiated newborn; Part VI. Assessing the Outcome of the Asphyxiated Infant: 40. Assessment of preterm infants' neurobehavrioural functioning: reliability, validity, normative data, and prediction to age two; 41. Long-term follow-up of term infants with perinatal asphyxia; 42. Appropriateness of intensive care application; 43. Medicolegal issues in perinatal brain injury; Index.