PET in Clinical Oncology

PET in Clinical Oncology describes the use of Positron Emission Tomography (PET) in the diagnosis and management of malignant tumors. Experts present the basics, technical details, and clinical aspects for both standard and new PET techniques. The book illustrates the importance of PET in comparison to other imaging techniques. Generously supplemented with charts, tables and illustrations, each chapter provides the reader with well-delineated descriptions, from the basic technical situation to the clinical use of PET. Essential for all those dealing with the diagnosis and therapy of cancer, especially nuclear medicine specialists and oncologists.

I. Basics: Physics, Chemistry, Camera techniques.- 1 Current status of PET in the United States.- 2 Physics, quality control.- 3 Image reconstruction, quantification and standard uptake value.- 4 Partial volume effects/corrections.- 5 Radiation safety in PET.- 6 FDG: biochemical concept and radiochemical synthesis.- 7 Current developments of 18F-labeled PET tracers in oncology.- 8 Cerium-doped lutetium oxyorthosilicate: a fast, efficient new scintillator.- 9 Optimization of gamma camera coincidence systems for PET in oncology.- 10 Combined PET/CT imaging using a single, dual-modality tomograph: a promising approach to clinical oncology of the future.- II Clinical application.- 11 Brain tumors.- 12 The role of FDG-PET in the management of oral squamous cell carcinoma (ICD-O-Da M-8070/3).- 13 PET in head and neck tumors.- 14 Carcinoma of unknown primary.- 15 Thyroid carcinomas.- 16 Lung cancer.- 17 Pancreatic cancer.- 18 Hepatobiliary tumors.- 19 Colorectal carcinomas.- 20 Hodgkin and Non-Hodgkin lymphoma.- 21 Testicular cancer.- 22 Prostate cancer.- 23 Malignant melanoma.- 24 Musculoskeletal tumors.- 25 Metastatic bone disease.- 26 Renal cell and urothelial cancer.- 27 Endocrine/neuroendocrine tumors.- 28 Breast cancer.- 29 Ovarian cancer.- 30 Pitfalls in the interpretation of PET studies.- 31 Monitoring of gene therapy with PET.- List of Radiopharmaceuticals.