Steroid Receptors in Health and Disease

I. Introduction and Keynote Address.- 1. Steroid Receptors in Health and Disease.- 2. Steroid Receptors: A Historical Perspective.- II. Receptor Structure and Molecular Organization.- 3. Intracellular Localization of Steroid Hormone Receptors: Immunocytochemical Analysis.- 4. Immunocytochemistry of Estrogen and Progestin Receptors in the Primate Reproductive Tract.- 5. Structure, Functional Domains and Subcellular Distribution of Glucocorticoid Receptor.- 6. Hormone-Dependent Phosphorylation of the Avian Progesterone Receptor.- III. Receptor Modifications and Hormone Regulation.- 7. Hormone-Dependent and Hormone-Independent Conformational Transitions of the Estrogen Receptor.- 8. Human Progesterone Receptors A and B: Two Independent, Functional Forms.- 9. Androgen Regulation of Gene Expression: Studies of Ornithine Decarboxylase in Murine Kidney.- 10. Advances in Uterus Estradiol Receptor Phosphorylation on Tyrosine and Preliminary Evidences that Liver Glucocorticoid Receptor Might Be Phosphorylated on Tyrosine.- IV. Receptor Gene Structure and Function.- 11. Functional Analysis of the Estrogen and Progesterone Receptors.- 12. Molecular Determinants of Positive and Negative Regulation by Ligand-Regulated Transcription Factors.- 13. The Mammalian Progesterone Receptor: Cloning, Immunolocalization and Mechanism of Interaction with DNA.- 14. Isolation and Sequence of the Human Glucocorticoid Receptor Gene Promoter. Cloning of the Human Androgen Receptor cDNA.- V. Biochemical Actions and Antihormones.- 15. Estrogen and Antiestrogen Regulation of Proliferation and Protein Synthesis of Human Breast Cancer Cells.- 16. An Estrogen Induced Protease in Breast Cancer: From Basic Research to Clinical Applications.- 17. Nuclear Acceptor Sites: Interaction with Estrogen-Versus Antiestrogen-Receptor Complexes.- 18. Antisteroid Hormones, Receptor Structure and Heat-Shock Protein MW 90,000 (hsp 90).- VI. Pharmacological and Clinical Correlations.- 19. Neural Estrogen and Progestin Receptors and the Neurochemistry of Reproductive Behavior and Sexual Differentiation.- 20. Estrogen Actions on Endometrial Adenocarcinoma.- 21. Structural Features and Clinical Significance of Estrogen Receptors.- 22. The Role of the Ras Oncogene in Human Mammary Cancer.- Author Index.