GI Epidemiology – Diseases and Clinical Methodology 2e

Nicholas J. Talley, University of Newcastle, Callaghan, NSW, Australia G. Richard Locke III, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA Paul Moayyedi, McMaster University, Hamilton, ON, Canada Joe West, Leeds Teaching Hospital Trust, University of Nottingham, Nottingham, UK Alexander C. Ford, Leeds General Infirmary, Leeds, UK Yuri A. Saito, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA

Contributors, viii Foreword, xiv Preface, xv About the companion website, xvi Part 1: Gastrointestinal Diseases and Disorders: The Public Health Perspective 1 The Burden of Gastrointestinal and Liver Disease Around the World, 3 Hannah P. Kim, Seth D. Crockett, & Nicholas J. Shaheen Part 2: How to Critically Read the Gastrointestinal Epidemiology Literature Introduction and Overview, 17 Joe West 2 How to Read a Cohort Study, 18 Laila J. Tata 3 How to Read a Case-Control Study, 30 Joe West, Laila J. Tata, & Timothy R. Card 4 How to Read a Randomized Controlled Clinical Trial, 39 Matthew J. Grainge 5 How to Read a Systematic Review and Meta-Analysis, 48 Alexander C. Ford & Paul Moayyedi 6 How to Decide if Any of This Matters, 58 Kate M. Fleming & Timothy R. Card Part 3: How to Do Clinical Research in GI 7 How to Develop and Validate a GI Questionnaire, 67 Enrique Rey & G. Richard Locke III 8 How to Do Population-Based Studies and Survey Research, 75 Sanjiv Mahadeva & Hematram Yadav 9 How to Find and Apply Large Databases for Epidemiologic Research, 83 Jonas F. Ludvigsson, Joe West, Jessica A. Davila, Timothy R. Card, & Hashem B. El-Serag 10 How to Do Genetic and Molecular Epidemiologic Research, 98 Yuri A. Saito 11 Diagnostic Studies, 106 Paul Moayyedi 12 Randomized Controlled Trials, 113 Paul Moayyedi & Richard H. Hunt Part 4: Epidemiology of Major GI Diseases 13 Epidemiology of GERD, Barrett s Esophagus and Esophageal Cancer, 121 David Armstrong 14 Epidemiology of Helicobacter Pylori Infection, Peptic Ulcer Disease and Gastric Cancer, 135 Grigorios I. Leontiadis & Olof Nyr'en 15 Epidemiology of Dyspepsia, 158 Alexander C. Ford & Nicholas J. Talley 16 Epidemiology of Upper Gastrointestinal Bleeding, 172 Colin J. Crooks, Joseph Sung, & Timothy R. Card 17 Epidemiology of Celiac Disease, 185 Alberto Rubio-Tapia, Jonas F. Ludvigsson, & Joseph A. Murray 18 Measuring Utilization of Endoscopy in Clinical Practice, 196 Frances Tse & Alan Barkun 19 Epidemiology of Colorectal Carcinoma, 213 Harminder Singh, Joselito M. Montalban, & Salaheddin Mahmud 20 Epidemiology of Irritable Bowel Syndrome, 222 Rok Seon Choung & Yuri A. Saito 21 Epidemiology of Constipation, 235 Brian E. Lacy & John M. Levenick 22 Epidemiology of Diverticular Disease, 249 Robin Spiller & David Humes 23 Epidemiology of Infectious Diarrhea, 262 Christina M. Surawicz & Crenguta Stepan 24 Epidemiology of Inflammatory Bowel Disease, 273 Edward V. Loftus, Jr. 25 Epidemiology of Fecal Incontinence, 285 Adil E. Bharucha 26 Epidemiology of Gallstones and Biliary Tract Cancers, 296 Guy D. Eslick & Eldon A. Shaffer 27 Epidemiology of Pancreatitis, 306 Dhiraj Yadav, Santhi Swaroop Vege, & Suresh T. Chari 28 Epidemiology of Pancreatic Cancer, 313 Aravind Sugumar & Santhi Swaroop Vege 29 Epidemiology of Hepatitis B and C in the United States, 322 Sumeet K. Asrani & W. Ray Kim 30 Epidemiology of Alcoholic Liver Disease, 332 Sumeet K. Asrani & William Sanchez 31 Epidemiology of Cirrhosis and Hepatocellular Carcinoma, 344 Joe West & Guruprasad P. Aithal 32 Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD), 357 Guruprasad P. Aithal, Kshaunish Das, & Abhijit Chowdhury 33 Epidemiology of Common Tropical GI Diseases, 373 Magnus Halland, Rodney Givney, & Anne Duggan 34 Nutritional Epidemiology and GI Cancers, 383 Linda E. Kelemen & Ilona Csizmadi 35 The Epidemiology of Obesity Among Adults, 394 Cynthia L. Ogden, Brian K. Kit, Tala H.I. Fakhouri, Margaret D. Carroll, & Katherine M. Flegal Index 405