Endothelium

Ayse Basak Engin, Atilla Engin

Physiological importance of endothelium. Vascular fluid mechanics in the regulation of endothelial function. Ultrastructure of endothelium and endothelial microparticules. Origin of endothelial progenitor cells and their functions. Endothelial dysfunction, cytokines and their genetic variations. Oxidative stress and endothelium: Cellular signaling, nitric oxide and reactive radicals. Asymmetric dimethylarginine and endothelial dysfunction. Endothelial Dysfunction and Diabetes Mellitus. Obesity, metabolic syndrome and endothelium. Vascular endothelium and renin-angiotensin system. Endothelial dysfunction in chronic kidney disease patients and renal transplant recipients: Emerging diagnostic and therapeutic options. Homocysteine and endothelial dysfunction. Oxidative stress and angiogensisis in tumor progression. Nanoparticle: As a messenger between environment and endothelium.