Chromosomal Aberrations -

Chromosomal Aberrations

Basic and Applied Aspects

Günter Obe, A.T. Natarajan (Herausgeber)

Buch | Softcover
XIII, 319 Seiten
2011 | 1. Softcover reprint of the original 1st ed. 1990
Springer Berlin (Verlag)
978-3-642-75684-9 (ISBN)
106,99 inkl. MwSt
Chromosomale Mutationen sind eine der m glichen Ursachen f}r
Ver{nderungen der Erbinformation. Neben grunds{tzlichen As-
pekten, wie Reparaturmechanismen der Zelle oder Ursachen von
Chromosomenver{nderungen, werden angewandte Aspekte, z.B.
Chromosomen als Testindikatoren der Toxizit{t, behandelt.

Quantitative Detection of Chromosome Structures by Computerized Microphotometric Scanning.- Heterogeneity of DNA Repair in Relation to Chromatin Structure.- The Poly-ADP-Ribosylation System of Higher Eukaryotes: How Can It Do What?.- DNA Lesions, DNA Repair, and Chromosomal Aberrations.- Is It Misrepair or Lack of Repair Which Kills Cells Irradiated in G2?.- Inhibitors of DNA Topoisomerases and Chromosome Aberrations.- Restriction Endonuclease- and Radiation-Induced DNA Double-Strand Breaks and Chromosomal Aberrations: Similarities and Differences.- The Use of Restriction Endonucleases to Study the Mechanisms of Chromosome Damage.- Induction of Chromosomal Aberrations by the Restriction Endonuclease Alul in Chinese Hamster Ovary (CHO) Cells: Influence of Glycerol on Aberration Frequencies.- Patterns of Chromosome Variations in Neoplasia.- Tumorigenesis and Tumor Response: View from the (Prematurely Condensed) Chromosomes.- Detection of Cancer-Prone Individuals Using Cytogenetic Response to X-Rays.- Human Disorders with Increased Spontaneous and Induced Chromosomal Instability.- Possible Causes of Variability of the Adaptive Response in Human Lymphocytes.- Adaptation of Human Lymphocytes to Radiation or Chemical Mutagens: Differences in Cytogenetic Repair.- Radio-Adaptive Response: A Novel Chromosomal Response in Chinese Hamster Cells in Vitro.- On Adaptive Response of Plant Meristem Cells in Vivo - Protection Against Induction of Chromatid Aberrations.- Chromosome Aberrations in A-Bomb Survivors, Hirsohima and Nagasaki.- Biological Dosimetry of Absorbed Radiation Dose: Considerations of Low-Level Radiations.- Use of Micronuclei in Biological Dosimetry of Absorbed Radiation Dose.- Biological Dosimetry After Radiation Accidents.- Dose Estimates and the Fate ofChromosomal Aberrations in Cesium-137 Exposed Individuals in the Goiania Radiation Accident.- Cytogenetic Studies in Male Germ Cells, Their Relevance for the Prediction of Heritable Effects and Their Role in Screening Protocols.- Use of in Vivo Micronucleus Tests with Mammalian Cells for Clastogenicity and Carcinogenicity Studies.- In Vitro Chromosomal Aberration Test - Current Status.- Clastogenesis in Vitro Under Extreme Culture Conditions.- Life-Style and Genetic Factors that Determine the Susceptibility to the Production of Chromosome Damage.

Erscheint lt. Verlag 13.12.2011
Zusatzinfo XIII, 319 p.
Verlagsort Berlin
Sprache englisch
Maße 170 x 242 mm
Gewicht 576 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Cell • chromosome • Chromosomen • Chromosomes • DNA • DNA repair • Influence • Lymphocytes • mutagen • Mutagenicity • Mutagenizität • Mutation • Mutationen • Screening • Stem Cells • Tumor • Tumorigenesis • Vivo
ISBN-10 3-642-75684-0 / 3642756840
ISBN-13 978-3-642-75684-9 / 9783642756849
Zustand Neuware
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