Tissue and Cell Processing

Deirdre Fehily PhD Inspector and Technical Advisor, Tissues and Cells, National Transplant Centre, Rome, Italy Scott A. Brubaker CTBS Chief Policy Officer, American Association of Tissue Banks, McLean, Virginia, USA John N. Kearney BSc, PhD, CBiol, MIBiol, SRCS Head of Tissue Services/Lead Scientist/PI for Research, Liverpool Blood Centre, NHS Blood & Transplant, Liverpool, UK Lloyd Wolfinbarger Jr. PhD BioScience Consultants, llc, Norfolk, Virginia, USA

List of Contributors Foreword Preface 1 Regulations and Standards Michael Cox and Scott A. Brubaker 2 Risk management in Tissue & Cell Processing Diane Wilson and Johann Kurz 3 Principles of Cell Collection and Tissue Recovery Helen Gillan, Derwood Pamphilon, Scott A. Brubaker 4 Principles of Cell and Tissue Cryopreservation Ying C. Song and David E. Pegg 5 Principles of tissue decontamination and sterilization Lloyd Wolfinbarger, Jr. and Pierre Lory 6 Control of Contamination and Cross Contamination During Processing: Optimising the Processing Environment Lisa Nair, Marisa Roma Herson and Kyle Bennett 7 The Principles of Process Validation and Equipment Qualification Martell Winters and Richard Lomas 8 Biomechanical and Biocompatibility Testing Considerations Caroline A Hartill 9 Coding and Traceability Stefan Poniatowski, Izabela Uhrynowska-Tyszkiewicz and Ineke Slaper-Cortenbach 10 Training of Tissue Bank Personnel Marti Manyalich, Debbie Butler Newman, Jacinto Sanchez Ibanez, Aurora Navarro, Gloria Paez, & Aziz Nather 11 Cardiac Tissue: Specific Recovery and Processing Issues Alyce Linthurst Jones, Robert Parker, Linda Manning and Helmi Albrecht 12 Skin: specific recovery and processing issues Elisa Pianigiani and Jan L. Pierce 13 Ophthalmic tissues: recovery and processing issues Diego Ponzin, Patricia Dahl and Elisabeth Pels 14 Skeletal Tissue: Specific Recovery and Processing Issues Joel Osborne, Art Kurz, Esteve Trias and Oscar Farinas 15 Processing of cells for transplantation Mark W Lowdell & Edward Samuel 16 Gametes and embryos: specific collection and processing issues Montserrat Boada and Anna Veiga 17 Engineering of human tissue grafts John N. Kearney and Francisco da Costa