The Molecular Immunology of Complex Carbohydrates-3 (eBook)

Dr. Wu has been studying on lectin–glycan interactions for more than 35 years, especially the recognition factors of lectins. He is the senior editor of the Molecular Immunology of Complex Carbohydrates 1 and 2 (Adv. Exp. Med. Biol. 228 and 491). Lectin recognition index is his ongoing project.

Part 1: Introduction to Glyco-Experiences Chp 1: Serendipity in Scientific Discoveries: Some Examples in GlycosciencesChp 2: My 30 Years Devotion to the N-linked Oligosaccharide Structures Part 2: Blood group ABH/Le-related antigensChp 3: Human Blood Group ABH/Ii, Lea, b, x, y and Sialyl Lea, x Glycotopes, Internal Structures and Immunochemical Roles of Human Ovarian Cyst GlycoproteinsChp 4: Lewis Glyco-Epitopes: Structure, Biosynthesis and FunctionsChp 5: An Unique Endo--Galactosidase that Cleaves Both Blood Group A and B Glycotopes Part 3: Lectins      Chp 6: Recognition Intensities of Mammalian Structural Units, Ligand Clusters and Polyvalency in the Lectin-Glycan Interaction ProcessesChp 7: Adhesion/Growth-Regulatory Galectins: Insights into their Ligand Selectivity Using Natural Glycoproteins and GlycotopesChp 8: Glycotope Structures and Intramolecular Affinity Factors of Plant Lectins for Tn/T AntigensChp 9: The Five Bacterial Lectins (PA-IL, PA-IIL, RSL, RS-IIL and CV-IIL) – Interactions with Diverse Animal Cells and GlycoproteinsChp 10:       On the Differential Sialic Acid Specificity of Lectins from Different Parts of Saraca indicaChp 11:       Regulation of Lectin Production by the Human Pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: Effects of Choline, Trehalose and EthanolChp 12:       Non-Carbohydrate Mediated Interaction of Lectins with Plant ProteinsChp 13:       Novel Concepts about the Role of Lectins in the Plant Cell Part 4: Structures and Functions of Glycolipids Chp 14:       Role of Gangliosides and of Plasma Membrane Associated Sialidase in the Process of Cell Membrane OrganizationChp 15:       9-O-Acetyl GD3 in Lymphoid and Erythroid CellsChp 16:       GM3 Up-Regulation of Matrix Metalloproteinase-9 (MMP-9) Possibly through PI3K, AKT, RICTOR, RhoGDI-2 and TNF-α Pathways in Mouse Melanoma B16 CellsChp 17:       Pathological Roles of Ganglioside Mimicry in Guillain-Barré Syndrome and Related NeuropathiesChp 18:       Structure and Function of Glycolipids in Thermophilic BacteriaChp 19:       Lipooligosaccharides (LOSs) of Neisseria Species: Similarity between N. Polysaccharea and N. Meningitidis LOSs Part 5: Structures and Functions of Complex Carbohydrates     Chp 20:       Roles for N- and O-Glycans in Early Mouse DevelopmentChp 21:       Glycobiology in the Field of Gerontology (Glycogerontology)Chp 22:       Galectins in Regulation of ApoptosisChp 23:       Avian and Human Influenza Virus Receptors and their DistributionChp 24:       Importance of a Factor VIIIc-Like Glycoprotein Expressed in Capillary Endothelial Cells (eFactor VIIIc) in AngiogenesisChp 25:       Mucin O-Glycan Branching Enzymes: Structure, Function and Gene RegulationChp 26:       Studying the Carbohydrate Self-Recognition in Marine Sponges Using Synthetic Aggregation Factor EpitopesChp 27:       Docking of Chitin Oligomers and Nod Factors on LysM Lectin Domains of the LysM-RLK Receptors as a First Recognition Step for the Establishment of the Medicago truncatula-Rhizobium Symbiosis Part 6: Glyco-Immunology   Chp 28:       O-Acetylated Sialic Acids and their Role in Immune DefenceChp 29:       Sialylated and Sulfated Carbohydrate Ligands for Selectins and Siglecs – Involvement in Traffic and Homing of Human Memory T- and B- LymphocytesChp 30:       Diversity of Natural Anti--Galactosyl Antibodies in Human SerumChp 31:       Prospective Highlights of Serum Glycoprotein Profiles in Spontaneous Tolerance after Liver Allograft Transplantation Part 7: Glycobiology of Cancer    Chp 32:       Hematogenous Metastasis: Roles of CD44v and Alternative Sialofucosylated Selectin LigandsChp 33:       Regulation of Glycosyltransferase Genes in Apoptotic Breast Cancer Cells Induced by L-PPMP and cis-PlatinChp 34:       Aberrant Glycosphingolipid Expression and Membrane Organization in Tumor Cells. Consequences on Tumor-Host InteractionsChp 35:       Human KDN (Deaminated Neuraminic Acid) and its Elevated Expression in Cancer Cells – Mechanism and SignificanceChp 36:       Polysialic Acid Bioengineering of Cancer and Neuronal Cells by N-Acyl Sialic Acid Precursor Treatment Part 8: Glyco-Applications Chp 37:       Synthesis of Hemagglutinin-Binding TrisaccharidesChp 38:       Fabrication and Applications of Glyco-NanomaterialsChp 39:       Glycan Arrays to Decipher the Specificity of Plant LectinsChp 40:       Targeting C-Type Lectin for the Treatment of Flavivirus Infections APPENDIX      INDEX