CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues (eBook)

Dedications 5
Foreword 14
Introduction 15
Acknowledgement 17
Contents 18
Radiation ( and Medical) Biosurveillance: Screening Survivors for Late Effects of Therapy Using the Children’s Oncology Group Long- Term Follow- Up Guidelines 20
Medical Countermeasures to Radiation Injury: Science and Service in the Public Interest 29
Ionizing Radiation and the Endothelium – A Brief Review 36
Inflammation and Cell Adhesion Molecules are Involved in Radiation- Induced Lung Injury 40
Volume Effects in Radiation Damage to Rat Lung 48
The Role of Imaging in the Study of Radiation- Induced Normal Tissue Injury 54
Screening for Cardiovascular Disease in Survivors of Thoracic Radiation 63
Hypoxia- Mediated Chronic Normal Tissue Injury: A New Paradigm and Potential Strategies for Intervention 76
Prevention and Treatment of Radiation Injuries – The Role of the Renin- Angiotensin System 83
Second Malignancies as a Consequence of Radiation Therapy 91
Using Quality of Life Information to Rationally Incorporate Normal Tissue Effects into Treatment Plan Evaluation and Scoring 96
Cancer- Related Fatigue as a Late Effect: Severity in Relation to Diagnosis, Therapy, and Related Symptoms 103
Normal Tissue TNM Toxicity Taxonomy: Scoring the Adverse Effects of Cancer Treatment 111
Cancer Survivorship Research: State of Knowledge, Challenges and Opportunities 120
Subject Index 142
List of Contributors 147