Hematopoietic Stem Cell Transplantation (eBook)
XVI, 736 Seiten
Humana Press (Verlag)
978-1-59745-438-4 (ISBN)
Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.
Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.
Preface 6
Acknowledgements 8
Contents 9
Contributors 12
Biology of Transplantation 16
Stem Cell Biology 17
Stem Cell Transplantation for Hematologic Malignancies 33
Immunobiology of Transplantation 53
Transplantation for Specific Disorders 69
Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia in the Adult 70
Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia 96
Stem Cell Transplantation for Hodgkin’s and Non-Hodgkin’s Lymphomas 118
Transplantation in Chronic Lymphocytic Leukemia 150
Stem Cell Transplantation in Multiple Myeloma 161
Allogeneic Hematopoietic Cell Transplantation for Patients with Myelodysplastic Syndrome and Myeloproliferative Disorders 179
Stem Cell Transplantation for Marrow Failure 195
Stem Cell Transplantation for Hemoglobinopathies 213
Alternative Stem Cell Sources 234
Stem Cell Sources for Allogeneic Transplantation 235
Allogeneic Unrelated Donor Blood and Marrow Transplantation 255
Umbilical Cord Hematopoietic Stem Cell Transplantation 276
Haploidentical Stem Cell Transplantation 298
Conditioning Regimens 327
Ablative Preparative Regimens for Hematopoietic Stem Cell Transplantation 328
Nonmyeloablative Transplantation 355
Complications of Transplantation 381
Immune Reconstitution after Allogeneic Transplantation 382
Infection in the Hematopoietic Stem Cell Transplant Recipient 426
EBV Lymphoproliferative Disease after Transplantation 454
Hepatic Veno-Occlusive Disease 471
Lung Injury after Hematopoietic Stem Cell Transplantation 498
Quality of Life Issues Post-Transplantation 540
Graft-versus-Host-Disease 563
Pathophysiology of Acute Graft-versus-Host Disease 564
Acute Graft-versus-Host Disease 590
Chronic Graft-versus-Host Disease 622
Immune Modulation 651
Graft Manipulation: T Cell Depletion and Tumor Cell Purging 652
Donor Lymphocyte Infusions. Clinical Applications and the Graft–versus-Leukemia Effect 686
Future Uses of Hematopoietic Stem Cells 710
Regenerative Medicine: Application in Cardiovascular Diseases 711
Index 723
| Erscheint lt. Verlag | 14.11.2008 |
|---|---|
| Reihe/Serie | Contemporary Hematology | Contemporary Hematology |
| Zusatzinfo | XVI, 736 p. 17 illus. in color. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Schlagworte | Acute Lymphoblastic Leukemia • Allogeneic Stem Cell Transplantation • Blood • Bone marrow • Cell • Cell Biology • Chronic Myelloid Leukemia • Graft-versus-Host Disease • Graft versus Leukemia Effect • Hematologic Malignancies • hematopoietic stem cell • hematopoietic stem cell transplantation • leukemia • Lymphoma • multiple myeloma • Myelodysplastic Syndrome • prevention • Regenerative medicine • Stem Cell • Stem Cell Biology • Stem Cells • stem cell transplantation • Transplantation • Tumor |
| ISBN-10 | 1-59745-438-9 / 1597454389 |
| ISBN-13 | 978-1-59745-438-4 / 9781597454384 |
| Haben Sie eine Frage zum Produkt? |
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