Cancer in the Spine (eBook)

Preface 6
Contents 7
Contributors 9
Cancer of the Spine 11
Metastatic Disease to the Musculoskeletal System 16
The Pathophysiology of Spinal Metastases 26
Tumor Behavior 33
Fundamentals of Cancer Treatment 39
The Role of Surgical Therapy 51
Presenting History and Common Symptoms of Spine Tumors 57
Physical Examination 62
Imaging 74
Imaging of the Spine 80
Laboratory Studies and Diagnostic Work- Up of Bony Lesions in the Spine 89
Principles of Medical Management 98
Multiple Myeloma and Plasmacytoma 106
Lymphoma 112
Metastatic Breast Carcinoma 121
Genitourinary Oncology 126
Spinal Metastases From Gastrointestinal Malignancies 134
Lung Cancer 143
Medical Management of Thyroid Cancer 158
Carcinoma of the Unknown Primary 166
Primary Tumors of the Spine 171
Common Radiotherapy Techniques for Spinal Tumors 188
Spinal Radiotherapy for the Pediatric Patient 196
Conformal Radiotherapy for Spinal Lesions 204
Photon- and Proton- Beam Radiotherapy in the Treatment of Spine Tumors 210
Spinal Metastasis 218
Biopsy 225
Problem- Based Decision Making 230
Spinal Cord and Nerve Root Decompression 235
Metastatic Disease of the Cervical Spine 243
Metastatic Disease of the Thoracolumbar Spine 251
Complex Lumbosacral Resection and Reconstruction Procedure 261
Neoplastic Disease of the Spinal Cord and the Spinal Canal 274
Minimally Invasive Approaches to Spinal Metastases 280
Single- Stage Posterolateral Transpedicle Approach With Circumferential Decompression and Instrumentation for Spinal Metastases 289
Primary Benign Spinal Tumors 297
Surgical Treatment of Primary Malignant Tumors 305
Complications of Surgical and Medical Care 316
Bracing for Patients With Spinal Tumors 330
Rehabilitation in Patients With Tumors of the Spinal Column 335
The Management of Pain in Spinal Malignancies 340
Surveillance and Screening During Disease- Free Survival 351
When Is Enough, Enough? 355
Index 361