Short-Term Bioassays in the Analysis of Complex Environmental Mixtures IV

Keynote Address.- Keynote Address.- Session 1: New Developments and Techniques.- Use of the Microscreen Assay for Airborne Particulate Organic Matter.- Development of an InSitu Test System for Detection of Mutagens in the Workplace.- Perturbations of Enzymic Initiation of Excision Repair Due to Guanine Modification in DNA.- Plant Genetic Assays to Evaluate Complex Environmental Mixtures.- Studies with Gaseous Mutagens in DrosophilaMelanogaster.- Anaphase Aberrations: An InVitro Test for Assessing the Genotoxicity of Individual Chemicals and Complex Mixtures.- Anaphase Aberrations: An InVivo Measure of Genotoxicity.- Measurement of Chemically Induced Mitotic Nondisjunction Using a Monochromosomal Human/Mouse Hybrid Cell Line.- Toxicologic Responses to a Complex Coal Conversion By-Product: Mammalian Cell Mutagenicity and Dermal Carcinogenicity.- Increased Virus Transformation by Formaldehyde of Hamster Embryo Cells Pretreated with Benzo(a)pyrene.- Enhancement of Anchorage-Independent Survival of Retrovirus-Infected Fischer Rat Embryo Cells for Determining the Carcinogenic Potential of Chemical and Physical Agents.- Correlation Between InVivo Tumorigenesis and InVitro Cytotoxicity in CHO and V79 Cells After Exposure to Mineral Fibers.- Quality Assurance and Good Laboratory Practice Regulations for Short-Term Bioassays of Complex Mixtures.- Generation and Characterization of Complex Gas and Particle Mixtures for Inhalation Toxicologic Studies.- Session 2: Integrated Assessment.- Nitro Compounds in Environmental Mixtures and Foods.- The Effect of Atmospheric Transformation Upon the Bacterial Mutagenicity of Airborne Organics: The EPA Experience.- Mutagenicity Studies of New Jersey Ambient Air Particulate Extracts.- Interurban Variations in the Mutagenic Activity of the Ambient Aerosol and Their Relations to Fuel Use Patterns.- Mutagenicity Analyses of Industrial Effluents: Results and Considerations for Integration into Water Pollution Control Programs.- Isolation of Mutagenic Compounds from Sludges and Wastewaters.- Session 3: Risk Assessment.- Application of Short-Term Tests in Monitoring Occupational Exposure to Complex Mixtures.- An Integrated Approach to Human Monitoring.- Human Cytogenetic Monitoring: Occupational Exposure to Ethylene Oxide.- Direct Mutagen Risk Assessment: The Development of Methods to Measure Immunologic and Genetic Responses to Mutagens.- Risk Assessment of Complex Mixtures.- Comparative Potency of Complex Mixtures: Use of Short-Term Genetic Bioassays in Cancer Risk Assessment.