Hypertension — 1972

Opening Remarks: The Remarkable Story of Hypertension.- Session 1.- Effects of Sympathetic Activity and ACTH on Renin and Aldosterone Secretion.- Contrived Suppression of Renin Secretion During Sodium Depletion.- Mechanism of Increased Renin Secretion Associated with Adrenalectomy, Hemorrhage, Renal Artery Constriction, and Sodium Depletion.- A Comparison of the Effects of Various Catecholamines on Plasma Renin Activity Alone and in the Presence of Adrenergic Blocking Agents.- In Vitro Renin Release by Human Kidney Slices: Effect of Norepinephrine, Angiotensin II and I, and Aldosterone.- Summary of Discussions.- New Observations on Renin Release by the Non-Filtering Kidney.- Functional and Enzymatic Analyses of Single Juxtaglomerular Apparatuses.- Studies on the Intrarenal Action of the Renin-Angiotensin System.- Renin and Renal Function.- Structural and Ultrastructural Alterations in Mesenteric and Renal Arterioles Following Infusion of Vaso-Active Agents.- Summary of Discussions.- Session 2.- Paradoxical Response of Plasma Renin Activity to Change in Sodium Intake in Hypertensive Patients.- The Relationship between Adrenergic Nervous System and Renin in Labile Hyperkinetic Hypertension.- Effect of Upright Posture on Cyclic AMP Excretion in Control Subjects and Patients with Essential Hypertension.- Reduction of Renal Mass and Hypertension.- Stimulatory Action of Various Drugs on Plasma Renin Activity and Angiotensin II Concentration in Normals, Patients with Arterial Hypertension and Congestive Heart Failure.- Summary of Discussions.- Session 3.- Multiple Forms of Human Kidney Renin.- The Nature of Renal Renin.- The Liver and the Renin Angiotensin System: The Effects of Common Bile Duct Ligature on Blood Pressure, Juxtaglomerular Apparatus and Renin Activity in Rats.-Corticotensins: Pressor Peptides from the Kidney.- Summary of Discussions.- Session 4.- The Role of Cations, ATP and Vasoactive Substances on the Activity of Contractile Proteins of Arteries.- Electron Microscopic Study of Arterial Lesions in Experimental Hypertension.- Effects of Angiotensin II on DNA, RNA and Protein Synthesis.- Circadian Aspects of Hormone and Electrolyte Metabolism in Hypertension.- Dynamic Changes in Plasma Aldosterone and Cortisol Levels and Renin Activity in Patients with Oligosymptomatic Adrenocortical Hypertension Simulating Essential Hypertension.- Summary of Discussions.- Session 5.- Aldosterone, Deoxycorticosterone, and Corticosterone Metabolism in Benign Essential Hypertension.- Secretion, Distribution and Turnover of Aldosterone in Essential Hypertension, Primary Aldosteronism, and Hypertension Associated with Renal Artery Stenosis.- Renin and Aldosterone in the Etiology and Prognosis of Essential Hypertension: Their Relation to Vascular Complications.- Aldosterone Responses to Volume Manipulation: Normal Man, Hypertension.- Incomplete Suppression of Aldosterone Secretion and Plasma Concentration in Hypertensive Patients on High Sodium Intake.- Plasma Progesterone Levels and 18-Hydroxydeoxycorticosterone Secretion Rate in Benign Essential Hypertension in Humans.- Summary of Discussions.- Session 6.- Photoscanning of Tumors in Primary Aldosteronism: Possible Distinction from "Idiopathic" Aldosteronism.- A Review of Spironolactone Therapy in Patients with Hypertension, Aldosterone Excess and Low Plasma Renin. Increased Desoxycortico- sterone in Hypertension - Another Variant of the Mineralocorticoid Excess Syndrome.- Mineralocorticoid Hypertension: Recognition and Results of Treatment.- The Influence of Glucocorticoids and Heparin onAldosterone Production.- Summary of Discussions.- Session 7.- Some Genetically Determined Differences between Hypertension-Prone and Hypertension-Resistant Rats.- 18-Hydroxy-11-Deoxycorticosterone (18-OH-DOC) Secretion in Experimental and Human Hypertension.- The Effect of Dietary Sodium on the Blood Pressure of Normotensive Man.- Summary of Discussions.- Session 8.- The Cortico-Medullary Zone of the Adrenal and the Hypertensive Process.- Interaction between the Separate Pressure Control Systems in Normal Arterial Pressure Regulation and in Hypertension.- Antihypertensive Action of the Renal Papilla.- Calcium Dependence of Vascular Smooth Muscle from Normotensive and Hypertensive Rats.- Analysis of Some Responses to Angiotensin in Vitro.- Summary of Discussions.- Session 9.- Preparation of Hog Renin Free of Pseudorenin.- An Intrinsic Renin-Angiotensin System in the Brain.- Subcellular Localization of Cerebral Renin-Like Activity.- Arterial and Urinary Renin Activity.- Body Composition in Primary and Secondary Hypertension.- Pseudo-Primary Aldosteronism, a Variant of Low Renin, Essential Hypertension?.- Summary of Discussions.- Session 10.- The Role of Angiotensin in Benign and Malignant Experimental Hypertension: an Immunological Approach.- Increased Aldosterone in Response to Sodium Deficiency in the Angiotensin II-Immunized Rabbit.- Salt, Hypertension and Cerebral Hemorrhages with Reference to Acute Vascular Lesions.- Angiotensin Receptors in Smooth Muscle Cells.- Summary of Discussions.- Session 11.- Human Lung Converting Enzyme.- A New "Angiotensin I Converting Enzyme" System.- Sites of Conversion of Angiotensin I.- Studies in Vitro of Angiotensin-Converting Enzyme of Lung and Other Tissues.- Inhibition of Converting Enzyme by Venom Peptides.- Summary ofDiscussions.- Clinical and Conceptual Uses of Angiotensin Receptors.- Sites and Mechanisms of Conversion of Angiotensin I to II.- Radioimmunoassay for Angiotensin I: Measurement of Plasma Renin Activity, Plasma Renin Concentration, Renin Substrate Concentration, and Angiotensin I, in Normal and Hypertensive People.- The Radio-Immunoassay of Angiotensin II and Plasma Renin Activity in Human Hypertension.- Radioimmunoassay Studies of the Renin-Angiotensin System in Human Hypertension and During Estrogen Treatment.- Summary of Discussions.- Concluding Remarks.- List of Authors.