Stratum Corneum

Prof. Dr. med. Gerd Plewig, Ärztlicher Direktor des Klinikums der Ludwig-Maximilians-Universität München (2002-2006).

I. Biochemistry.- The Fibrous Proteins of the Epidermis.- Isolation and Characterisation of Different Keratin Types From Human Epidermis.- Cross-Linking of Epidermal Fibrous Protein.- Epidermal Keratin: Filaments and Matrix.- Control of Involucrin Synthesis During Terminal Differentiation of Human Epidermal Cells in Culture.- The Synthesis, Fate and Function of Histidine-Rich Proteins in the Stratum Corneum.- The Intercorneocyte Space.- Preparation and Immunochemical Analysis of Non-Ionic Detergent-Soluble Protein From Human Stratum Corneum.- Isolation and Lipid Composition of Fractions From the Superficial Stratum Corneum of the Pig.- Epidermal Cholesterol Sulfate and Steroid Sulfatase Activity and Recessive X-linked Ichthyosis.- DNase I - Actin Interaction in the Epidermis and Its Influence on Epidermal Metabolism.- II. Aspects of the Immunology of the Stratum Corneum.- Stratum Corneum Antigens: Their Role in Psoriasis and in the Autoimmune Repair Mechanisms.- Natural Stratum Corneum Antibodies and Antigens.- Localisation of Non-Ionic Detergent-Soluble Stratum Corneum Antigens in Human Epidermis.- The Immunotracing of Keratinocyte Subsets.- III. Structure and Function.- The Cellular Architecture of the Stratum Corneum.- Effects of Frictional Stimulation on the Structure of the Stratum Corneum.- The Significance of the Size and Shape of Corneocytes.- Thickness of Corneocytes.- Age-Related Changes in Stratum Corneum, Structure and Function.- Exfoliative Cytology: Effects of the Seasons.- Scanning Electron Microscopy of Human Corneocytes.- Corneocyte Size as An Indirect Measure of Epidermal Proliferative Activity.- Corneocyte Formation Rate and Skin Disease.- Skin Scales and Microbial Contamination.- The Transparency of the Stratum Corneum as A Parameter of FunctionalAnalysis.- Transmission of UV Radiation Through Horny Layer and Epidermis in Relation to the Minimal Erythema Dose (MED).- Elemental Distribution in Cross Sections of Guinea-pig Epidermis: X-ray Microanalysis in the Electron Microscope.- IV. Pharmacological Topics.- Effects of Isotretinoin (13-cis Retinoic Acid, Ro 4-3780) Treatment on Exfoliative Cytology.- Follicular Keratinization.- Druc-Induced Changes in Stratum Corneum Production Traced by Human Antibodies in Murine Tails.- Changes in Corneocyte Size After Application of Topical Corticosteroids and Vehicles to Normal Skin.- Water Sorption - Desorption Test of the Stratum Corneum of the Skin Surface in Vivo.- Electical Measurement of the Hydration State of the Skin Surface in Vivo.- The Relationship Between Conductance and Capacitance Measurements and Skin Surface Contour During Hydration of the Stratum Corneum.