Dementia, 4th Edition

David Ames BA MD FRCPsych FRANZCP Professor of Ageing and Health National Ageing Research Institute University of Melbourne, Parkville, Victoria, Australia Alistair Burns MPhil MD FRCP FRCPsych Professor of Old Age Psychiatry University of Manchester, Manchester, UK John O'Brien MA DM, FRCPsych Professor of Old Age Psychiatry Institute for Ageing and Health, Newcastle University Newcastle upon Tyne, UK

Dementia: General Aspects
Dementia: historical overview
The lived experience of dementia
Prevalence and incidence of dementia
Criteria for the diagnosis of dementia
Assessment of the patient with apparent dementia
Screening and assessment instruments for the detection and measurement of cognitive impairment
Neuropsychological assessment of dementia
Neuropsychiatric aspects of dementia
Measurement of neuropsychiatric symptoms, behavioural disturbance and quality of life
Cross-cultural issues in the assessment of cognitive impairment
Structural brain imaging
Functional brain imaging and connectivity in dementia
Molecular brain imaging in dementia
The neurophysiology of dementia
Family carers of people with dementia
One caregivers view
Dementia care in the community: challenges for primary health and social care
Managing co-morbidities and general hospital admissions for people with dementia
The role of nursing in the management of dementia
Social work and care/case management in dementia
Occupational therapy in dementia care
The role of the speech and language therapist in the assessment and management of the person with dementia
The role of physiotherapy in the management of dementia
Therapeutic effects of music in people with dementia
Non-pharmacological therapies to manage behavioural and psychological symptoms of dementia: what works and what doesn't
A predominantly psychosocial approach to behaviour problems in dementia: treating causality
Drug treatments for the behavioural and psychiatric symptoms of dementia
Psychological approaches for the practical management of cognitive impairment in dementia
Sexuality and dementia
Residential care for people with dementia
Design and dementia
Legal issues and dementia
Driving and dementia
Quality of life in dementia: conceptual and practical issues
Ethical issues and dementia
End-of-life decisions and dementia
Care and management of the patient with advanced dementia
Alzheimer associations and societies
Health economic aspects of dementia
The global challenge of dementia: what can be done
Development of a national strategy for dementia: dementia and policy in the UK
The pharmaceutical industry and dementia: how can clinicians, researchers and industry work together ethically for the betterment of people with dementia and their families?

Mild cognitive impairment
Mild cognitive impairment: a historical perspective
Clinical characterization of mild cognitive impairment
Managing the patient with mild cognitive impairment

Alzheimer’s disease
What is Alzheimer’s disease?
Risk factors for Alzheimer’s disease
The natural history of Alzheimer’s disease
The neuropathology of Alzheimer’s disease
Neurochemistry of Alzheimer's disease
The central role of amyloid in the pathogenesis of Alzheimer's disease
Genetics of Alzheimer's disease
Blood and cerebrospinal fluid biomarkers for Alzheimer’s disease
Established treatments for Alzheimer's disease: cholinesterase inhibitors and memantine
Drug treatments in development for Alzheimer’s disease
Stem cell therapies for Alzheimer’s disease and other dementias
Vitamins and complementary therapies used to treat Alzheimer’s disease
Prevention of Alzheimer’s disease
Trial designs

The overlap and interaction between Alzheimer's disease and cerebrovascular disease
Vascular factors and Alzheimer’s disease

Cerebrovascular disease and cognitive impairment
What is vascular cognitive impairment?
The neuropathology of vascular dementia
Therapeutic strategies for vascular dementia and vascular cognitive disorders

Dementia with Lewy bodies and Parkinson’s disease
Dementia with Lewy bodies: a clinical and historical overview
Pathology of dementia with Lewy bodies
The treatment of dementia with Lewy bodies
Cognitive impairment and dementia in Parkinson’s disease

Focal dementias and related issues
Frontotemporal dementia
Pick's disease: its relationship to progressive aphasia, semantic dementia and frontotemporal dementia
The genetics and molecular pathology of frontotemporal lobar degeneration
Semantic dementia
Primary progressive aphasia and posterior cortical atrophy
The cerebellum and cognitive impairment

Other dementias and neuropsychiatric disorders associated with cognitive impairments
Depression with cognitive impairment
Schizophrenia, cognitive impairment and dementia
Dementia in intellectual disabilities
Alcohol-related dementia and Wernicke-Korsakoff syndrome
Huntingdon’s disease
Creutzfeldt-Jakob disease and other prion diseases
Uncommon forms of dementia