Pediatric Hematology and Oncology

Edward J. Estlin, BSc (Hons), PhD, MRCP, FRCPCH Macmillan Consultant in Paediatric Oncology, Department of Paediatric Oncology, Royal Manchester Children s Hospital, Manchester, UK Richard J. Gilbertson, B.Med.Sci (Hons), MRCP, PhD Co-Leader, Neurobiology and Brain Tumor Program; Director, Molecular Clinical Trials Core, Departments of Developmental Neurobiology and Oncology, St Jude Children s Research Hospital, Memphis, TN, USA Robert F. Wynn, BA, MD, MRCP, FRCPath Consultant Paediatric Haematologist and Programme Director, Blood and Marrow Transplant Unit, Royal Manchester Children s Hospital, Manchester, UK

Contributors. 1 Introduction (Edward J. Estlin, Richard J. Gilbertson and Robert F. Wynn). Part I Central Nervous System Tumors of Childhood. 2 Low- and High-Grade Glioma (Ian F. Pollack). 3 Ependymoma (Thomas E. Merchant and Richard J. Gilbertson). 4 Embryonal Tumors (Amar Gajjar and Steven C. Clifford). 5 Pediatric Spinal Cord Tumors (Annie Huang, Ute Bartels and Eric Bouffet). 6 Pediatric Craniopharyngioma, Mixed Glioneuronal Tumors, and Atypical Teratoid/Rhabdoid Tumor (Adrienne Weeks and Michael D. Taylor). Part II Hematological Disorders. 7 Acute Lymphoblastic Leukemia (Robert F. Wynn). 8 Acute Myeloid Leukemia and Myelodysplastic Disorders (David K.H. Webb). 9 Non-Hodgkin s Lymphoma (Angelo Rosolen and Lara Mussolin). 10 Hodgkin's Lymphoma (Wolfgang Dorffel and Dieter Korholz). 11 Histiocytic Disorders (Sheila Weitzman and R. Maarten Egeler). Part III Solid Tumors of Childhood. 12 Neuroblastoma (Sucheta J. Vaidya and Andrew D. J. Pearson). 13 Renal Tumors (Edward J. Estlin and Norbert Graf). 14 Soft Tissue Sarcoma (Gianni Bisogno and John Anderson). 15 Bone Tumors (Richard Gorlick, Martha Perisoglou and Jeremy Whelan). 16 Hepatic Tumors (Penelope Brock, Derek J. Roebuck and Jack Plaschkes). 17 Germ Cell Tumors (James Nicholson and Roger Palmer). 18 Retinoblastoma (Edward J. Estlin, Francois Doz and Michael Dyer). 19 Rare Tumors (Bernadette Brennan and Charles Stiller). Part IV Supportive Care, Long-Term Issues, and Palliative Care. 20 Supportive Care: Physical Consequences of Cancer and its Therapies (Bob Phillips and Roderick Skinner). 21 Psychosocial Needs of Children with Cancer and Their Families (Ged Lalor and Louise Talbot). 22 Late Effects in Relation to Childhood Cancer (Louise Talbot and Helen Spoudeas). 23 Palliative Care (Lynda Brook). 24 Clinical Trials Involving Children with Cancer Organizational and Ethical Issues (Sue Ablett and Edward J. Estlin). Index. Colour plate.