Addiction Reviews 2, Volume 1187

George R. Uhl, NIDA, NIH, Baltimore, MD.

Introduction to Addiction reviews 2 / by George R. Uhl 1 Preface to Addiction reviews 2 / by George F. Koob 3

Part I. Medications for addiction and relevant neurotransmitter systems.

Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders / by Christian A. Heidbreder and Amy H. Newman 4

Cocaine-induced neuroadaptations in glutamate transmission : potential therapeutic targets for craving and addiction / by Heath D. Schmidt and R. Christopher Pierce 35

Agonist-like pharmacotherapy for stimulant dependence : preclinical, human laboratory, and clinical studies / by David V. Herin, Craig R. Rush and John Grabowski 76

Part II. Drug and HIV toxicities

Amphetamine toxicities : classical and emerging mechanisms / by Bryan K. Yamamoto, Anna Moszczynska and Gary A. Gudelsky 101

Human immunodeficiency virus-associated neurocognitive disorder : pathophysiology in relation to drug addiction / by Avindra Nath 122

Part III. Physiology.

Synaptic plasticity in the mesolimbic system : therapeutic implications for substance abuse / by Billy T. Chen, F. Woodward Hopf and Antonello Bonci 129

Electrophysiological correlates of abused drugs : relation to natural rewards / by Sam A. Deadwyler 140

Part IV. Imaging.

Neurochemistry of drug action : insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction / by Stephanie C. Licata and Perry F. Renshaw 148

Part V. Development.

Cocaine addiction in mothers : potential effects on maternal care and infant development / by Lane Strathearn and Linda C. Mayes 172

Part VI. Genetics.

Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment / by Vadim Yuferov [and others] 184

Addictions and their familiality in Iceland / by Thorarinn Tyrfingsson [and others] 208

Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs / by Ichiro Sora [and others] 218

Part VII. Behavioral mechanisms.

Conditioned taste aversion learning : implications for animal models of drug abuse / by Catherine M. Davis and Anthony L. Riley 247

Part VIII. Comorbidity.

The strong relationship between bipolar and substance-use disorder : mechanisms and treatment implications / by Alan C. Swann 276

Part IX. Nonsubstance addictions.

Shared brain vulnerabilities open the way for nonsubstance addictions : carving addiction at a new joint? / by Joseph Frascella [and others] 294

Part X. Molecules for addiction.

Regulation of the dopamine transporter : aspects relevant to psychostimulant drugs of abuse / by Kyle C. Schmitt and Maarten E.A. Reith 316

Regulator of G protein-signaling proteins and addictive drugs / by John Traynor 341

Part XI. Epidemiology.

Novel phenotype issues raised in cross-national epidemiological research on drug dependence / by James C. (Jim) Anthony 353

Part XII. Places and institutions.

Office of National Drug Control Policy: A scientist in drug policy in Washington, DC / by Bertha K. Madras. 370