Dendrites
Oxford University Press (Verlag)
978-0-19-856656-4 (ISBN)
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Dendrites form the major receiving part of neurons. It is within these highly complex, branching structures that the real work of the nervous system takes place. The dendrites of neurons receive thousands of synaptic inputs from other neurons. However, dendrites do more than simply collect and funnel these signals to the soma and axon; they shape and integrate the inputs in complex ways. Despite being discovered over a century ago, dendrites received little research attention until the early 1950s. Over the past few years there has been a dramatic explosion of interest in the function of these beautiful structures. Recent new research has developed our understanding of the properties of dendrites, and their role in neuronal function. The first edition of Dendrites was a landmark in the literature, stimulating and guiding further research. The new edition substantially updates the earlier volume, and includes 5 new chapters and colour illustrations. Its gathers new information on dendrites into a single volume, with contributions written by leading researchers in the field.It presents a survey of the current state of our knowledge of dendrites, from their morphology and development through to their electrical, chemical, and computational properties.
As such it will not only be of interest to researchers and graduate-level students in neuroscience, but will also be useful to researchers in computer science and IT, psychology, physiology, and biophysics.
1. Dendrite structure; 2. Evolution and scaling of dendrites; 3. Dendrite development; 4. Molecular determinants of dendrite and spine development; 5. RNA targeting, trafficking and translation in dendrites: contribution to synaptic tagging and plasticity; 6. Organization and regulation of the post-synaptic density; 7. Subcellular distribution of neurotransmitter receptors and voltage-gated ion channels; 8. Neurotransmitter-gated ion channels in dendrites; 9. Dendritic voltage-gated ion channels; 10. Biochemical compartmentalization in dendrites; 11. Spine calcium signaling; 12. An historical perspective on modeling dendrites; 13. A theoretical view of the neuron as an input-output plastic device; 14. Dendritic integration; 15. Dendrites as transmitters; 16. Why have dendrites? A computational perspective; 17. Short stories about small brains: linking biophysics to computation; 18. Functional plasticity at dendritic synapses; 19. Structural plasticity of dendrites; 20. Dendrites and disease; 21. Conclusion: the future of dendrites
Erscheint lt. Verlag | 27.9.2007 |
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Zusatzinfo | 53 line illustrations, 26 black & white photographs and 25 colour illustrations |
Verlagsort | Oxford |
Sprache | englisch |
Maße | 171 x 246 mm |
Gewicht | 1400 g |
Themenwelt | Geisteswissenschaften ► Psychologie ► Test in der Psychologie |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 0-19-856656-5 / 0198566565 |
ISBN-13 | 978-0-19-856656-4 / 9780198566564 |
Zustand | Neuware |
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